High Serum Ferritin Levels among Blood Transfused Thalassemic Patients Admitted to the Department of Paediatrics in a Tertiary Care Centre: A Descriptive Cross-Sectional Study

Introduction: Raised serum ferritin levels often indicate iron overload, but they are not specific as the elevated in inflammatory disorders, liver diseases, alcohol excess, or malignancy. If regular transfusions required for patient with thalassemia, this doubles rate of accumulation leading to earlier massive overload and iron-related damage. The aim study aimed find out prevalence high among blood-transfused thalassemic patients admitted Department Paediatrics a tertiary care centre. Methods: A descriptive cross-sectional was conducted at centre from 1 March 2022 31 December 2022. Ethical approval taken Institutional Review Committee (Reference number: 078/79-017/HG). Children who were confirmed by haemoglobin electrophoresis on blood transfusion included study. Those did gave consent excluded Convenience sampling method used. Point estimate 90% Confidence Interval calculated. Results: Out 53 cases, level seen 46 (88.79%) (80.30-97.28, 95% Interval). Among 46, 34 (73.91%) had more than 1000 2500 ng/ml whereas 12 (26.09%) 25000 ng/ml. Conclusions: transfused found be higher other studies done similar settings.